2-Bromo-N,N-diphenylaniline synthesis
- Product Name:2-Bromo-N,N-diphenylaniline
- CAS Number:78600-31-4
- Molecular formula:C18H14BrN
- Molecular Weight:324.21
122-39-4
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$14.00/5g
583-53-9
326 suppliers
$10.00/5g
78600-31-4
145 suppliers
$10.00/250mg
Yield:78600-31-4 73%
Reaction Conditions:
with copper(l) iodide;18-crown-6 ether in 1,2-dichloro-benzene at 100 - 210;Inert atmosphere;Darkness;
Steps:
1 Example 1: Synthesis of N-(2-bromophenyl)-N-diphenylamine
Diphenylamine (1.6900 g, 10.0 mmol), o-dibromobenzene (2.40 mL, 20.0 mmol), copper iodide (0.1900 g, 1.0 mmol), 18-crown-6 (0.1320 g, 0.5 mmol), and 60 mL of o-dichlorobenzene were sequentially added to the reaction flask. Under nitrogen protection and dark conditions, stir and heat to 100-210°C for 5-100 hours. Stop the reaction and slowly reduce to room temperature, vacuum distillation of most of the solvent, suction filtration, The solid residue is washed with dichloromethane solution and the organic phases are combined. Concentration and column chromatography gave N-2-bromophenyl-N-diphenylamine (yield: 73%)
References:
Xinyang Normal University;Zhao Xianghua;Li Xiaosheng;Tang Lin;Wang Limin CN107417676, 2017, A Location in patent:Paragraph 0037; 0038
583-55-1
484 suppliers
$7.00/5g
122-39-4
358 suppliers
$14.00/5g
78600-31-4
145 suppliers
$10.00/250mg