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2-CHLORO-5,8-DIMETHOXY-3-PHENYLQUINOLINE synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: pyridine / CH2Cl2 / 2 h / Ambient temperature
2: POCl3 / 4 h / 90 °C

References:

Gazit, Aviv;App, Harald;McMahon, Gerald;Chen, Jefferey;Levitzki, Alexander;Bohmer, Frank D. [Journal of Medicinal Chemistry,1996,vol. 39,# 11,p. 2170 - 2177]