2-CHLOROBUTYRAMIDE synthesis
- Product Name:2-CHLOROBUTYRAMIDE
- CAS Number:7462-73-9
- Molecular formula:C4H8ClNO
- Molecular Weight:121.57
4170-24-5
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7462-73-9
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$22.39/1g
Yield:7462-73-9 94.5%
Reaction Conditions:
with thionyl chloride;ammonia in tert-butyl methyl ether;water at 0; for 5 h;Time;
Steps:
1.3 Example 3:
In a 1000 ml reaction flask,82.7 g of 2-chlorobutyric acid, 247.5 g of 30% aqueous ammonia and 500 ml of methyl t-butyl ether were added, and the mixture was cooled to 0 ° C, a solution of 82.5 g of thionyl chloride was slowly added dropwise,After completion of the dropwise addition, the reaction was incubated for 5 hours. After the completion of the reaction,The organic layer was washed with water and concentrated to dryness to give 78 g of 2-chlorobutanamide.
References:
CN106187809,2016,A Location in patent:Paragraph 0008; 0016; 0018
4158-37-6
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7462-73-9
45 suppliers
$22.39/1g