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2'-Deoxy-2'-fluoro-L-uridine synthesis

9synthesis methods
2,4(1H,3H)-Pyrimidinedione, 1-[2-deoxy-2-fluoro-3,5-bis-O-(tetrahydro-2H-pyran-2-yl)-β-L-ribofuranosyl]-

323193-78-8
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2'-Deoxy-2'-fluoro-L-uridine

622785-69-7
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Yield:622785-69-7 83%

Reaction Conditions:

with Amberlite (H+) in methanol;water at 20;

References:

Dantsu, Yuliya;Zhang, Wen;Zhang, Ying [Organic Letters,2021,vol. 23,# 13,p. 5007 - 5011] Location in patent:supporting information