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2'-DEOXY-4-DESMETHYLWYOSINE synthesis

1synthesis methods
-

Yield:101803-00-3 82%

Reaction Conditions:

Stage #1: 2'-Deoxyguanosinewith sodium hydride in dimethyl sulfoxide at 20; for 1 h;
Stage #2: 1-bromoacetone in dimethyl sulfoxide at 20; for 1 h;

References:

Hofmann, Tatjana;Zweig, Karin;Engels, Joachim W. [Synthesis,2005,# 11,art. no. T14304SS,p. 1797 - 1800]