2-Fluoro-3-methoxyphenylacetic acid synthesis
- Product Name:2-Fluoro-3-methoxyphenylacetic acid
- CAS Number:863645-29-8
- Molecular formula:C9H9FO3
- Molecular Weight:184.16
672931-80-5
8 suppliers
inquiry
863645-29-8
13 suppliers
$45.00/10mg
Yield:863645-29-8 96.4%
Reaction Conditions:
with sodium hydroxide in ethanol;water at 40 - 100;
Steps:
5 Example 5
Compound V (40.2 g, 0.24 mmol), ethanol (200 mL),Water (200 mL), sodium hydroxide (29.2 g, 0.73 mol) was added, and the temperature was raised to 40-100 ° C until the reaction was completed. Concentrated ethanol, washed with methyl tert-butyl ether, lowered the temperature to 0 to 10 ° C, adjusted the pH to 3 to 4 with dilute hydrochloric acid, and filtered and dried to obtain a light brown solid.Compound VI (43.2 g, 96.4%).
References:
CN110759870,2020,A Location in patent:Paragraph 0092; 0119; 0128-0129
1418126-60-9
2 suppliers
inquiry
863645-29-8
13 suppliers
$45.00/10mg
178974-59-9
46 suppliers
$44.00/1g
863645-29-8
13 suppliers
$45.00/10mg
103438-88-6
160 suppliers
$14.14/250mgs:
863645-29-8
13 suppliers
$45.00/10mg
178974-63-5
7 suppliers
inquiry
863645-29-8
13 suppliers
$45.00/10mg