2-Fluoro-4-(3-trifluoroMethylphenyl)benzoic acid synthesis
- Product Name:2-Fluoro-4-(3-trifluoroMethylphenyl)benzoic acid
- CAS Number:926222-59-5
- Molecular formula:C14H8F4O2
- Molecular Weight:284.21
1423-26-3
353 suppliers
$6.00/1g
112704-79-7
538 suppliers
$15.00/5G
926222-59-5
17 suppliers
$75.00/250mg
Yield:926222-59-5 84%
Reaction Conditions:
with potassium phosphate;tris-(dibenzylideneacetone)dipalladium(0);tricyclohexylphosphine in 1,4-dioxane at 100; for 1 h;Microwave irradiation;
References:
Calvet, Claudia M.;Vieira, Debora F.;Choi, Jun Yong;Kellar, Danielle;Cameron, Michael D.;Siqueira-Neto, Jair Lage;Gut, Jiri;Johnston, Jonathan B.;Lin, Li;Khan, Susan;McKerrow, James H.;Roush, William R.;Podust, Larissa M. [Journal of Medicinal Chemistry,2014,vol. 57,# 16,p. 6989 - 7005] Location in patent:supporting information