2-HYDROXY-3-METHOXYBENZAMIDE synthesis
- Product Name:2-HYDROXY-3-METHOXYBENZAMIDE
- CAS Number:26751-04-2
- Molecular formula:C8H9NO3
- Molecular Weight:167.16
6342-70-7
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$8.00/5g
26751-04-2
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$400.00/1g
Yield:26751-04-2 95%
Reaction Conditions:
with ammonia in methanol at 80; for 16 h;Sealed tube;
Steps:
17.4 Step 4: Preparation of 2-hydroxy-3-methoxybenzamide
The methyl 2-hydroxy-3-methoxybenzoate (1.62 g, 8.89 mmol) and 7N NH3 / MeOH (20 l) prepared in step 3 above were placed in a sealed-tube At 80 ° C And the mixture was stirred for 16 hours.The reaction mixture was cooled to room temperature and the reaction mixture was concentrated under reduced pressure. The resulting residue was purified by silica gel chromatography (n-Hex / EtOAc = 1/1) to obtain the target compound 2-hydroxy-3-methoxybenzamide (1.42 g, 95%).
References:
KR2018/56603,2018,A Location in patent:Paragraph 0441; 0458-0460
148-53-8
400 suppliers
$10.00/1g
26751-04-2
15 suppliers
$400.00/1g
877-22-5
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$8.00/10g
26751-04-2
15 suppliers
$400.00/1g