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490039-70-8

2-Iodo-3-Methoxybenzonitrile synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 2,2,6,6-tetramethylpiperidinyl-lithium / tetrahydrofuran; hexane / 0.01 h / 0 °C / Flow reactor
2: iodine / tetrahydrofuran / 0.17 h / Inert atmosphere; Flow reactor

References:

Ketels, Marthe;Ziegler, Dorothée S.;Knochel, Paul [Synlett,2017,vol. 28,# 20,p. 2817 - 2822]