2-Isobutyl-2H-pyrazole-3-boronic acid synthesis
- Product Name:2-Isobutyl-2H-pyrazole-3-boronic acid
- CAS Number:847818-64-8
- Molecular formula:C7H13BN2O2
- Molecular Weight:168
725746-81-6
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$65.00/1g
847818-64-8
31 suppliers
$107.00/100mg
Yield:847818-64-8 54%
Reaction Conditions:
Stage #1: 1-isobutyl-1H-pyrazolewith n-butyllithium in tetrahydrofuran;hexane at 5 - 20; for 1 h;
Stage #2: with Trimethyl borate in tetrahydrofuran;hexane at -70; for 0.5 h;
Stage #3: with ammonium chloride in tetrahydrofuran;hexane at -15 - 20; for 1 h;
References:
Ivachtchenko, Alexandre V.;Kravchenko, Dmitry V.;Zheludeva, Valentina I.;Pershin, Dmitry G. [Journal of Heterocyclic Chemistry,2004,vol. 41,# 6,p. 931 - 939]