2-Isobutylthiophene synthesis
- Product Name:2-Isobutylthiophene
- CAS Number:32741-05-2
- Molecular formula:C8H12S
- Molecular Weight:140.25
36448-60-9
24 suppliers
$31.00/250mg
32741-05-2
22 suppliers
inquiry
Yield:32741-05-2 83%
Reaction Conditions:
with hydrazine hydrate;potassium hydroxide in ethylene glycol at 210; for 3 h;
Steps:
162.b 2-isobutylthiophene
The thiophene -2 - isopropyl ketone (840 mg, 5 . 45 mmol), KOH (1.23 g, 21 . 92 mmol) and hydrazine hydrate (1.64 g, 32 . 76 mmol) is dissolved in ethylene glycol, heated to 210 degrees, reaction 3 h after, cooling to room temperature, diluted with water, diethyl ether extraction, the organic layer and then sequentially water, salt water washing, the combined organic layer, column separation to obtain light yellow oily matter (635 mg, 83%);
References:
CN107098846,2017,A Location in patent:Paragraph 2380; 2384; 2385
