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1254062-67-3

[2-methyl-4-(2-methylpropoxy)phenyl]methanol synthesis

1synthesis methods
4-isobutoxy-2-methylbenzaldehyde

1254062-66-2
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[2-methyl-4-(2-methylpropoxy)phenyl]methanol

1254062-67-3
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Yield:1254062-67-3 87%

Steps:



4-Isobutoxy-2- methylbenzaldehyde was converted to (4-Isobutoxy-2-methylphenyl)methanol in 87% yield. 1H-NMR (400 MHz, CDCl3) δ (ppm): 7.202-7.223 (dlH, J=8.4Hz), 6.700-6.750 (t, 3H, J=8.4Hz), 4.629 (s,2H), 3.700-3.717 (d, 2H, J=6.8Hz), 2.361 (s,3H), 2.038-2.104 (m,lH), 1.010-1.026 (d, 6H, J=6.4Hz).

References:

WO2010/127212,2010,A1 Location in patent:Page/Page column 41