2-Oxiraneoctanoic acid, methyl ester synthesis

Yield:87321-84-4 96.4%

Reaction Conditions:

with ethylbenzene hydroperoxide;molybdenum naphthenate in ethylbenzene at 200; for 3.5 h;Inert atmosphere;Reagent/catalyst;Solvent;Temperature;

Steps:

2 Example 2

200 grams of 9-decenoic acid methyl ester was added to the flask.506.6 g of B with 35.5 wt% ethylbenzene hydroperoxide (EBHP)a benzene solution and 1.84 g of molybdenum naphthenate, the flask was replaced with nitrogen three times, and reacted at 200 ° C for 3.5 hours.The conversion of methyl 9-decenoate by gas phase internal standard method and 1H NMR was 99.2%.The selectivity of 9,10-epoxymethane decanoate is 98.3%.Refining to obtain 209.5 g of pure 9,10-epoxymethyl decanoate,Starting from methyl 9-decenoate,The yield of 9,10-epoxymethane decanoate was 96.4%.

References:

CN108117479,2018,A Location in patent:Paragraph 0054; 0056; 0057; 0060; 0063; 0066; 0069; 0072