2-(PYRROLIDIN-3-YLOXY)-PYRIDINE synthesis

2synthesis methods

Product Name:2-(PYRROLIDIN-3-YLOXY)-PYRIDINE
CAS Number:253603-61-1
Molecular formula:C9H12N2O
Molecular Weight:164.2

372-48-5 Synthesis

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Yield:-

Steps:

Multi-step reaction with 2 steps
1: caesium carbonate / N,N-dimethyl-formamide / 150 °C
2: hydrogenchloride / ethyl acetate / 23 °C

References:

Liang, Jun;Labadie, Sharada;Zhang, Birong;Ortwine, Daniel F.;Patel, Snahel;Vinogradova, Maia;Kiefer, James R.;Mauer, Till;Gehling, Victor S.;Harmange, Jean-Christophe;Cummings, Richard;Lai, Tommy;Liao, Jiangpeng;Zheng, Xiaoping;Liu, Yichin;Gustafson, Amy;Van der Porten, Erica;Mao, Weifeng;Liederer, Bianca M.;Deshmukh, Gauri;An, Le;Ran, Yingqing;Classon, Marie;Trojer, Patrick;Dragovich, Peter S.;Murray, Lesley [Bioorganic and Medicinal Chemistry Letters,2017,vol. 27,# 13,p. 2974 - 2981]

Pyridine, 2-[[1-(phenylmethyl)-3-pyrrolidinyl]oxy]-

253603-60-0
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References

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