1,3-Benzenediamine, N1,N3-bis[4-(1,1-dimethylethyl)phenyl]- synthesis
- Product Name:1,3-Benzenediamine, N1,N3-bis[4-(1,1-dimethylethyl)phenyl]-
- CAS Number:202832-48-2
- Molecular formula:C26H32N2
- Molecular Weight:372.55
Yield:202832-48-2 80%
Reaction Conditions:
with palladium diacetate;sodium tertiary butoxide in toluene; for 24 h;Reflux;
Steps:
6-3 Synthesis Example 6-3. Synthesis of
1-Bromo-5-iodobenzene (59 g, 177 mmol), 4-tert-butylaniline (58 g, 389 mmol),Palladium acetate (1.6g, 7mmol), Sodium tert-butoxide (51g, 530mmol), Bis(diphenylphosphino)-1,1' -binaphthyl) (4.4 g, 7 mmol) and 500 mL of toluene were placed in a 1 L reactor and stirred under reflux for 24 hours. After the reaction was completed, the filtrate was filtered and concentrated. It was separated by column chromatography to obtain (52.8 g, yield 80%).
References:
CN113748106,2021,A Location in patent:Paragraph 0357-0359
