(2S,3S,4R)-3,4-Bis[(tert-butyldimethylsilyl)oxy]-2-hexacosanoylamino-4-octadecanol synthesis

6synthesis methods

Product Name:(2S,3S,4R)-3,4-Bis[(tert-butyldimethylsilyl)oxy]-2-hexacosanoylamino-4-octadecanol
CAS Number:205371-68-2
Molecular formula:C56H117NO4Si2
Molecular Weight:924.7

506-46-7 Synthesis

506-46-7
141 suppliers
$50.00/50mg

(2S,3S,4R)-3,4-Bis[(tert-butyldimethylsilyl)oxy]-2-hexacosanoylamino-4-octadecanol

205371-68-2
12 suppliers
$145.00/5mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1: 95 percent / EDCI / CH₂Cl₂ / 3 h / 40 °C
2: 95 percent / Et₃N / tetrahydrofuran / 14 h / 50 °C
3: 80 percent / 2,6-lutidine / CH₂Cl₂ / 2 h / 20 °C
4: 85 percent / aq. TFA / tetrahydrofuran / 2.5 h / -10 - 10 °C

References:

Kim, Sanghee;Song, Soyoung;Lee, Taeho;Jung, Sungkyu;Kim, Deukjoon [Synthesis,2004,# 6,p. 847 - 850]

22102-68-7 Synthesis