(2S)-3-methyl-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]butanoic acid synthesis
- Product Name:(2S)-3-methyl-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]butanoic acid
- CAS Number:21282-10-0
- Molecular formula:C10H16N2O4
- Molecular Weight:228.24
13518-40-6
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: triethylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 12 h / 0 - 20 °C
2: hydrogenchloride / 1,4-dioxane / 3 h / 20 °C
References:
Hirai, Shizuka;Horii, Sho;Matsuzaki, Yoshiaki;Ono, Shin;Shimmura, Yuki;Sato, Kenji;Egashira, Yukari [Life Sciences,2014,vol. 117,# 1,p. 1 - 6]