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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
24243-38-7

2-(morpholin-4-yl)ethyl(4E)-6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate synthesis

4synthesis methods
O-Desmethyl Mycophenolic Acid

31858-65-8
33 suppliers
$139.90/1mg

2-(morpholin-4-yl)ethyl(4E)-6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate

24243-38-7
17 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 3 steps
1: O-methyltransferase / aq. phosphate buffer; glycerol / 45 °C / pH 8 / Enzymatic reaction
2: boron tribromide / dichloromethane
3: O-methyltransferase / aq. phosphate buffer; glycerol / 45 °C / pH 8 / Enzymatic reaction

References:

Zhang, Wei;Cao, Shaona;Qiu, Li;Qi, Fengxia;Li, Zhong;Yang, Ying;Huang, Shaohua;Bai, Fali;Liu, Changning;Wan, Xiaobo;Li, Shengying [ChemBioChem,2015,vol. 16,# 4,p. 565 - 569]

MYCOPHENOLATE MOFETIL RELATED COMPOUND B [(RS)-7-HYDROXY-5-METHOXY-4-METHYL-6-[2-(5-METHYL-2-OXO-TETRAHYDROFURAN-5-YL)ETHYL]-3H-ISOBENZOFURANYL-1-ONE]

26675-76-3
49 suppliers
$295.00/10mg

2-(morpholin-4-yl)ethyl(4E)-6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate

24243-38-7
17 suppliers
inquiry

References
Mycophenolic acid

24280-93-1
489 suppliers
$5.00/100mg

2-(morpholin-4-yl)ethyl(4E)-6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate

24243-38-7
17 suppliers
inquiry

References
Mycophenolic acid

24280-93-1
489 suppliers
$5.00/100mg

MYCOPHENOLATE MOFETIL RELATED COMPOUND B [(RS)-7-HYDROXY-5-METHOXY-4-METHYL-6-[2-(5-METHYL-2-OXO-TETRAHYDROFURAN-5-YL)ETHYL]-3H-ISOBENZOFURANYL-1-ONE]

26675-76-3
49 suppliers
$295.00/10mg

2-(morpholin-4-yl)ethyl(4E)-6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate

24243-38-7
17 suppliers
inquiry

References

2-(morpholin-4-yl)ethyl(4E)-6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate Related Search:

Methyl Mycophenolate (EP Impurity E) 6-(4,6-DIHYDROXY-7-METHYL-3-OXO-1,3-DIHYDRO-ISOBENZOFURAN-5-YL)-4-METHYL-HEX-4-ENOIC ACID METHYL ESTER