(6-2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester synthesis
- Product Name:(6-2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-D5-pyrrol-1-yl]-ethyl-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
- CAS Number:265989-42-2
- Molecular formula:C40H42D5FN2O6
- Molecular Weight:675.8402
20012-63-9
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265989-42-2
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$504.04/5MG
Yield:-
Steps:
Multi-step reaction with 5 steps
1: 76 percent / toluene / Heating
2: β-alanine; glacial acetic acid / hexane / Heating
3: 3-ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide; triethylamine / ethanol / Heating
4: pivalic acid / tetrahydrofuran; toluene; heptane / Heating
5: 81 percent / hydrogen; acetic acid / palladium on carbon / ethyl acetate
References:
Chen, Bang-Chi;Sundeen, Joseph E.;Guo, Peng;Bednarz, Mark S.;Hangeland, Jon J.;Ahmed, Syed Z.;Jemal, Mohammed [Journal of labelled compounds and radiopharmaceuticals,2000,vol. 43,# 3,p. 261 - 270]
265989-41-1
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265989-42-2
13 suppliers
$504.04/5MG
4560-41-2
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265989-42-2
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265989-31-9
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265989-42-2
13 suppliers
$504.04/5MG
1020719-18-9
16 suppliers
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265989-42-2
13 suppliers
$504.04/5MG