ChemicalBook CAS DataBase List methyl 3-amino-3-[4-(trifluoromethoxy)phenyl]propanoate

methyl 3-amino-3-[4-(trifluoromethoxy)phenyl]propanoate synthesis

1synthesis methods

Product Name:methyl 3-amino-3-[4-(trifluoromethoxy)phenyl]propanoate
CAS Number:287959-34-6
Molecular formula:C11H12F3NO3
Molecular Weight:263.21

3-AMINO-3-(4-TRIFLUOROMETHOXY-PHENYL)-PROPIONIC ACID

213192-56-4
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methyl 3-amino-3-[4-(trifluoromethoxy)phenyl]propanoate

287959-34-6
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Yield:-

Reaction Conditions:

with thionyl chloride

Steps:

1.1 EXAMPLE 1

7.5 g of 3-amino-3-(4-trifluoromethoxyphenyl)propionic acid is activated with thionyl chloride (1.2 equivalent) and esterified with methanol at the boiling point under standard conditions. The usual workup results in methyl 3-amino-3-(4-trifluoromethoxyphenyl)propionate, FAB-MS (M+H)⁺ 263.

References:

US6576637,2003,B1

methyl 3-amino-3-[4-(trifluoromethoxy)phenyl]propanoate Related Search:

methyl 3-amino-3-[4-(trifluoromethyl)phenyl]propanoate

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