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ChemicalBook CAS DataBase List ethyl 4-(3-bromophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

ethyl 4-(3-bromophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate synthesis

1synthesis methods
3132-99-8 Synthesis
3-Bromobenzaldehyde

3132-99-8
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Carbamimidothioic acid

17356-08-0
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ethyl 4-(3-bromophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

294854-53-8
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Yield:294854-53-8 90%

Reaction Conditions:

with sulfuric acid immobilized on activated charcoal in hexane;acetonitrile; for 0.833333 h;Reflux;Biginelli pyrimidine synthesis;

References:

Dilmaghani, Karim Akbari;Zeynizadeh, Behzad;Parasajam, Hadi [Phosphorus, Sulfur and Silicon and the Related Elements,2012,vol. 187,# 4,p. 544 - 553] Location in patent:experimental part