
2H-PYRAZOLE-3-CARBALDEHYDE synthesis
- Product Name:2H-PYRAZOLE-3-CARBALDEHYDE
- CAS Number:3920-50-1
- Molecular formula:C4H4N2O
- Molecular Weight:96.09

111573-59-2

3920-50-1
The general procedure for the synthesis of 3-pyrazolecarboxaldehyde from 3-dimethoxymethyl-1H-pyrazole: 2.3 kg of formic acid was added slowly and dropwise to 15.5 kg of an aqueous solution containing 13.8 kg of 3-dimethoxymethyl-1H-pyrazole at 0-15 °C. Subsequently, the reaction mixture was magnetically stirred at 25 °C for 12 h. A light yellow solid was obtained upon completion of the reaction. The precipitate was separated by filtration and the filter cake was washed with 10 L of water to give 643 g of the final yellow solid product 3-pyrazolecarboxaldehyde.

23585-49-1
143 suppliers
$45.00/100mg

3920-50-1
250 suppliers
$9.00/1g
Yield:-
Reaction Conditions:
with manganese(IV) oxide in N,N-dimethyl-formamide at 70;
References:
Lee, Eun;An, Ying;Kwon, Junhee;Kim, Keun Il;Jeon, Raok [Bioorganic and Medicinal Chemistry,2017,vol. 25,# 14,p. 3614 - 3622]