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2H-Pyrrole-5-carbonitrile, 3,4-dihydro- synthesis

1synthesis methods
(S)-PYRROLIDINE-2-CARBONITRILE

204387-53-1
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2H-Pyrrole-5-carbonitrile, 3,4-dihydro-

108602-79-5
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Yield:108602-79-5 20%

Reaction Conditions:

with N-chloro-succinimide;triethylamine in dichloromethane at 0 - 20; for 3 h;Inert atmosphere;

References:

Yasukawa, Naoki;Yamanoue, Ami;Takehara, Tsunayoshi;Suzuki, Takeyuki;Nakamura, Shuichi [Chemical Communications,2022,vol. 58,# 9,p. 1318 - 1321] Location in patent:supporting information