ChemicalBook CAS DataBase List 3-(1-HYDROXYCYCLOHEXYL)-2-PROPYNOIC ACID

3-(1-HYDROXYCYCLOHEXYL)-2-PROPYNOIC ACID synthesis

7synthesis methods

Product Name:3-(1-HYDROXYCYCLOHEXYL)-2-PROPYNOIC ACID
CAS Number:25294-58-0
Molecular formula:C9H12O3
Molecular Weight:168.19

2-Propynoic acid, 3-(1-hydroxycyclohexyl)-, ethyl ester

76925-79-6
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3-(1-HYDROXYCYCLOHEXYL)-2-PROPYNOIC ACID

25294-58-0
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$359.00/500mg

Yield:25294-58-0 57%

Reaction Conditions:

with lithium hydroxide in tetrahydrofuran;water at 20; for 2 h;

References:

Krall, Jacob;Jensen, Claus Hatt;Bavo, Francesco;Falk-Petersen, Christina Birkedahl;Haugaard, Anne St?hr;Vogensen, Stine Byskov;Tian, Yongsong;Nittegaard-Nielsen, Mia;Sigurdardóttir, Sara Bj?rk;Kehler, Jan;Kongstad, Kenneth Thermann;Gloriam, David E.;Clausen, Rasmus Pr?torius;Harps?e, Kasper;Wellendorph, Petrine;Fr?lund, Bente [Journal of Medicinal Chemistry,2017,vol. 60,# 21,p. 9022 - 9039]

108-94-1 Synthesis