3-(1H-PYRAZOL-3-YL)ANILINE synthesis
- Product Name:3-(1H-PYRAZOL-3-YL)ANILINE
- CAS Number:89260-46-8
- Molecular formula:C9H9N3
- Molecular Weight:159.19
59843-77-5
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$15.00/250mg
89260-46-8
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$44.00/250mg
Yield:89260-46-8 96%
Reaction Conditions:
with hydrogen;palladium 10% on activated carbon in methanol at 20;
Steps:
7.12
3-(lH-pyrazol-3-yl)benzenamine (12.B). To a solution of 3-(3-nitrophenyl)- lH-pyrazole 12.A (490 mg, 2.59 mmol, available from Oakwood) in methanol (5 mL) was added 10% Pd on carbon by weight (100 mg). The air was evacuated from the reaction flask and was replaced with hydrogen. The resulting slurry was stirred overnight at room temperature. The reaction mixture was filtered, and the mother liquor condensed to afford 3- (lH-pyrazol-3-yl)benzenamine 12.B (397mg, 96% yield).
References:
WO2010/93849,2010,A2 Location in patent:Page/Page column 58
89260-45-7
47 suppliers
$40.00/100mg
20583-31-7
83 suppliers
$15.00/250mg
89260-46-8
49 suppliers
$44.00/250mg