ChemicalBook CAS DataBase List 3,3-DIFLUOROCYCLOBUTANAMINE HYDROCHLORIDE

3,3-DIFLUOROCYCLOBUTANAMINE HYDROCHLORIDE synthesis

5synthesis methods

Product Name:3,3-DIFLUOROCYCLOBUTANAMINE HYDROCHLORIDE
CAS Number:637031-93-7
Molecular formula:C4H8ClF2N
Molecular Weight:143.56

791061-00-2 Synthesis

791061-00-2
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$8.00/250mg

3,3-DIFLUOROCYCLOBUTANAMINE HYDROCHLORIDE

637031-93-7
225 suppliers
$6.00/100mg

Yield:637031-93-7 95%

Reaction Conditions:

with hydrogenchloride in ethanol;water at 10 - 15; for 8 h;Solvent;

Steps:

7; 8 Example 7: Synthesis of Compound 6
Add compound 5 (90g, 0.84mol) synthesized in Example 4 to a 250mL reaction flask, add 4M hydrochloric acid ethanol solution (540g) at 10-15°C, stir for 8 hours, concentrate under reduced pressure to dryness, add ethyl acetate ( 450 mL) was stirred for 1 hour, then filtered and dried in vacuum at 50°C to obtain 114.3 g of a white solid with a yield of 95% and a purity of 100%.

References:

CN112279785, 2021, A Location in patent:Paragraph 0034; 0062-0065

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