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3-(3-thienyl)pentanedioic acid synthesis

2synthesis methods
498-62-4 Synthesis
3-Thiophenecarboxaldehyde

498-62-4
393 suppliers
$5.00/1g

3-(3-thienyl)pentanedioic acid

154227-58-4
2 suppliers
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 75 percent / piperidine / 2 h / 0 °C
2: 52 percent / 7 M aq. KOH / 0.5 h / 90 °C

References:

Jilale;Netchitailo;Decroix;Vegh [Journal of Heterocyclic Chemistry,1993,vol. 30,# 4,p. 881 - 885]