3-(4-Methyl-1H-indol-1-yl)propan-1-aMine synthesis
1synthesis methods
- Product Name:3-(4-Methyl-1H-indol-1-yl)propan-1-aMine
- CAS Number:1094754-77-4
- Molecular formula:C12H16N2
- Molecular Weight:188.27
![5H-Pyrrolo[2',1':3,4][1,4]diazepino[1,2-a]indol-3(2H)-one, 1,6,7,13b-tetrahydro-12,13b-dimethyl-](/CAS/20210305/GIF/1385027-59-7.gif)
Yield:1385027-59-7 82%
Reaction Conditions:
Stage #1: 4-pentynoic acid;C12H16N2with 2-(di-tert-butylphosphino)-1,1'-biphenylgold(I) chloride in water at 150; for 0.5 h;Microwave irradiation;
Stage #2: with trifluoroacetic acid in water at 150; for 0.5 h;Microwave irradiation;
References:
Feng, Enguang;Zhou, Yu;Zhao, Fei;Chen, Xianjie;Zhang, Lei;Jiang, Hualiang;Liu, Hong [Green Chemistry,2012,vol. 14,# 7,p. 1888 - 1895] Location in patent:supporting information; experimental part