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ChemicalBook CAS DataBase List 3,6-PYRIDAZINEDICARBOXYLIC ACID

3,6-PYRIDAZINEDICARBOXYLIC ACID synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: hydrazine hydrate / ethanol / 10 h / 90 °C / Inert atmosphere
1.2: 10 h / 100 °C / Inert atmosphere
2.1: selenium(IV) oxide; pyridine / 16 h / 120 °C / Inert atmosphere

References:

THE SCRIPPS RESEARCH INSTITUTE;EXPANSION THERAPEUTICS, INC.;DISNEY, Matthew;BLIZZARD, Timothy, Allen;RZUCZEK, Suzanne;NDUNGU, John;VACCA, Joseph;JENNINGS, Andy;PUSHECHNIKOV, Alexei WO2019/99777, 2019, A2

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