3-bromobicyclo[1.1.1]pentane-1-carboxylic acid synthesis

2synthesis methods

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 95 percent / CF₃CHBrCl / 1 h / Irradiation
2: 86 percent / aq. sulfuric acid / tetrahydrofuran / 8 h / 50 °C

References:

Della, Ernest W.;Taylor, Dennis K. [Journal of Organic Chemistry,1994,vol. 59,# 11,p. 2986 - 2996]

83249-14-3 Synthesis

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