3-FLUORO-N-HYDROXY-BENZAMIDINE synthesis
- Product Name:3-FLUORO-N-HYDROXY-BENZAMIDINE
- CAS Number:54872-79-6
- Molecular formula:C7H7FN2O
- Molecular Weight:154.14
403-54-3
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$7.00/5g
54872-79-6
38 suppliers
$45.00/100mg
Yield: 100%
Reaction Conditions:
with hydroxylamine monohydrate in ethanol at 90; for 1 h;Sealed tube;
Steps:
4.1.4. General procedure for the synthesis of amidoximes (39e52)
General procedure: In a pressurized sealed vial, aqueous hydroxylamine 50% w/w (4equiv) was added to a stirred solution of the appropriate carbonitrile(1 equiv) in absolute ethanol. The resulting mixture washeated at 90 C for 1 h. The solvent was then evaporated to drynessproviding the desired amidoxime quantitatively, which was usedwithout further purification.
References:
Quadri, Marta;Silnović, Almin;Matera, Carlo;Horenstein, Nicole A.;Stokes, Clare;De Amici, Marco;Papke, Roger L.;Dallanoce, Clelia [European Journal of Medicinal Chemistry,2018,vol. 160,p. 207 - 228]
72505-20-5
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$46.00/500 mg
54872-79-6
38 suppliers
$45.00/100mg
1073-06-9
430 suppliers
$6.00/10g
54872-79-6
38 suppliers
$45.00/100mg
24964-64-5
318 suppliers
$9.00/1g
54872-79-6
38 suppliers
$45.00/100mg