3-methoxy-N1,N1-dimethylbenzene-1,4-diamine synthesis
- Product Name:3-methoxy-N1,N1-dimethylbenzene-1,4-diamine
- CAS Number:7474-82-0
- Molecular formula:C9H14N2O
- Molecular Weight:166.22
14703-82-3
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7474-82-0
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Yield:7474-82-0 94%
Reaction Conditions:
with hydrogen;palladium 10% on activated carbon in ethyl acetate; under 2585.81 Torr; for 0.5 h;
Steps:
163 Preparation of intermediate 2-methoxy-N,N-dimethyl-benzene-1,4-diamine
A suspension of 3-methoxy-N,N-dimethyl-4-nitroaniline (Bionet) (0.5 g, 2.6 mmol) and Pd/C (Aldrich, 10%, 0.1 g) in ethyl acetate (10 mL) was vigorously shaken in a Parr under atmosphere of H2 (50 psi) for 0.5 h. The mixture was filtered through a short pad of celite. The filtrate was concentrated to give 2-methoxy-N,N-dimethyl-benzene-1,4-diamine as a dark brown oil (0.4 g, 94%).
References:
US2011/130398,2011,A1 Location in patent:Page/Page column 72
![Acetamide,N-[4-(dimethylamino)-2-methoxyphenyl]-](/CAS/20180601/GIF/7475-00-5.gif)
7475-00-5
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7474-82-0
19 suppliers
$200.00/250mg
448-19-1
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7474-82-0
19 suppliers
$200.00/250mg