3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one synthesis
- Product Name:3-Methyl-1,3,4,5-tetrahydrobenzo[d]azepin-2-one
- CAS Number:73644-95-8
- Molecular formula:C11H13NO
- Molecular Weight:175.23
13156-97-3
13 suppliers
inquiry
73644-95-8
27 suppliers
inquiry
Yield:-
Reaction Conditions:
with aluminum (III) chloride at 90 - 150; for 6 h;
Steps:
13.a
(a) 1-methyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepine8.0 g (37 mmol) 2-chloro-N-(2-phenylethyl)-propanamide and 15 g (112 mmol) aluminium trichloride are carefully mixed at 90° C. and heated to 150° C. for 6 h. The mixture is diluted with water and methanol and extracted with EtOAc. The combined organic phases are dried with Na2SO4, concentrated i. vac. and purified by chromatography.
References:
US2009/48231,2009,A1 Location in patent:Page/Page column 15
13230-84-7
2 suppliers
inquiry
73644-95-8
27 suppliers
inquiry
![4,5-DIHYDRO-1H-BENZO[D]AZEPIN-2(3H)-ONE](/CAS/GIF/15987-50-5.gif)
15987-50-5
39 suppliers
inquiry
74-88-4
356 suppliers
$15.00/10g
74938-33-3
0 suppliers
inquiry
73644-95-8
27 suppliers
inquiry
589-08-2
129 suppliers
$31.80/1gm:
73644-95-8
27 suppliers
inquiry
![3-Azaspiro[5.5]undeca-7,10-dien-2-one, 9-hydroxy-3-methyl-](/CAS/20210305/GIF/117034-52-3.gif)
117034-52-3
0 suppliers
inquiry
73644-95-8
27 suppliers
inquiry