3'-(TRIFLUOROMETHYL)[1,1'-BIPHENYL]-2-CARBALDEHYDE synthesis
- Product Name:3'-(TRIFLUOROMETHYL)[1,1'-BIPHENYL]-2-CARBALDEHYDE
- CAS Number:223575-93-7
- Molecular formula:C14H9F3O
- Molecular Weight:250.22
![2-Propanamine, N-[(2-methoxyphenyl)methylene]-2-methyl-](/CAS/20210305/GIF/82632-38-0.gif)
Yield:223575-93-7 79%
Reaction Conditions:
Stage #1: N-tert-butyl-1-(2-methoxyphenyl)methaniminewith chromium dichloride in tetrahydrofuran at 25; for 0.0833333 h;Schlenk technique;Inert atmosphere;
Stage #2: 3-(trifluoromethyl)phenylmagnesium bromide in tetrahydrofuran at 25; for 5 h;Schlenk technique;Inert atmosphere;
Stage #3: with hydrogenchloride in tetrahydrofuran;water at 25; for 3 h;Schlenk technique;Inert atmosphere;
References:
Cong, Xuefeng;Tang, Huarong;Zeng, Xiaoming [Journal of the American Chemical Society,2015,vol. 137,# 45,p. 14367 - 14372] Location in patent:supporting information
1423-26-3
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6630-33-7
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223575-93-7
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444-29-1
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18982-54-2
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223575-93-7
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7022-45-9
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$22.00/250mg
223575-93-7
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135-02-4
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223575-93-7
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