Diethyl 2-(((4-(Methoxycarbonyl)Phenyl)Amino)Methylene)Malonate synthesis
1synthesis methods
- Product Name:Diethyl 2-(((4-(Methoxycarbonyl)Phenyl)Amino)Methylene)Malonate
- CAS Number:303120-71-0
- Molecular formula:C16H19NO6
- Molecular Weight:321.33
Yield:303120-71-0 98%
Reaction Conditions:
Stage #1: 2-[(4-carboxy-phenylamino)-methylene]-malonic acid diethyl esterwith potassium carbonate in acetone at 20; for 1 h;
Stage #2: methyl iodide in acetone at 20; for 2 h;
References:
Ilangovan, Andivelu;Kumar, Rajendran Ganesh [Chemistry - A European Journal,2010,vol. 16,# 9,p. 2938 - 2943] Location in patent:supporting information; experimental part