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4-Chloro-5-(2-chloro-ethyl)-6-methyl-pyrimidin-2-ylamine synthesis

1synthesis methods
-

Yield:306314-90-9 68%

Reaction Conditions:

with trichlorophosphate at 110; for 2 h;Chlorination;

References:

Gangjee;Yu;McGuire;Cody;Galitsky;Kisliuk;Queener [Journal of Medicinal Chemistry,2000,vol. 43,# 21,p. 3837 - 3851]