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ChemicalBook CAS DataBase List ETHYL 4-CHLORO-5,7-DIFLUOROQUINOXALINE-3-CARBOXYLATE
311346-69-7

ETHYL 4-CHLORO-5,7-DIFLUOROQUINOXALINE-3-CARBOXYLATE synthesis

4synthesis methods
228728-82-3 Synthesis
5,7-Difluoro-4-hydroxyquinoline-3-carboxylic acid ethyl ester

228728-82-3
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Yield:-

Reaction Conditions:

with trichlorophosphate in 1,4-dioxane at 120; for 1 h;

References:

Zhang, Yiqun;Clark, Julie A.;Connelly, Michele C.;Zhu, Fangyi;Min, Jaeki;Guiguemde, W. Armand;Pradhan, Anupam;Iyer, Lalitha;Furimsky, Anna;Gow, Jason;Parman, Toufan;El Mazouni, Farah;Phillips, Margaret A.;Kyle, Dennis E.;Mirsalis, Jon;Guy, R. Kiplin [Journal of Medicinal Chemistry,2012,vol. 55,# 9,p. 4205 - 4219] Location in patent:supporting information; experimental part

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