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ChemicalBook CAS DataBase List (2E,4S)-4-AMino-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid Ethyl Ester
328086-61-9

(2E,4S)-4-AMino-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid Ethyl Ester synthesis

7synthesis methods
328086-54-0 Synthesis
(2E,4S)-4-[(tert-Butyloxycarbonyl)aMino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid Eethyl Ester

328086-54-0
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Yield:328086-61-9 100%

Reaction Conditions:

with hydrogenchloride in ethanol at 20; for 1 h;

References:

Johnson, Theodore O.;Hua, Ye;Luu, Hiep T.;Brown, Edward L.;Chan, Fora;Chu, Shao Song;Dragovich, Peter S.;Eastman, Brian W.;Ferre, Rose Ann;Fuhrman, Shella A.;Hendrickson, Thomas F.;Maldonado, Fausto C.;Matthews, David A.;Meador III, James W.;Patick, Amy K.;Reich, Siegfried H.;Skalitzky, Donald J.;Worland, Stephen T.;Yang, Michelle;Zalman, Leora S. [Journal of Medicinal Chemistry,2002,vol. 45,# 10,p. 2016 - 2023]