5-BROMO-3-METHYLBENZO[B]THIOPHENE-2-SULPHONYL CHLORIDE synthesis
- Product Name:5-BROMO-3-METHYLBENZO[B]THIOPHENE-2-SULPHONYL CHLORIDE
- CAS Number:338797-11-8
- Molecular formula:C9H6BrClO2S2
- Molecular Weight:325.63
![5-BroMo-3-Methyl-benzo[b]thiophene](/CAS/GIF/1196-09-4.gif)
1196-09-4
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338797-11-8
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Yield:338797-11-8 39%
Reaction Conditions:
with chlorosulfonic acid in chloroform at -5 - 0;
Steps:
Chlorosulfonic acid (2.20 ml, 0.033 mmol) was added dropwise at -5 °C to a solution of 5- bromo-3-methylbenzothiophene (Intermediate 9) (3.0 g, 13.2 mmol) in CHCI3 (30 mL). The reaction mixture was stirred at 0 °C for 3 h, and then poured into a mixture of ice/NaHC03 and stirred vigorously for 5 min. The organic phase was immediately separated, dried and concentrated to give the title compound (1.70 g, 39%).
References:
WO2012/35171,2012,A2 Location in patent:Page/Page column 50
106-53-6
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338797-11-8
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$44.00/250mg
1200-12-0
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338797-11-8
20 suppliers
$44.00/250mg