2,4(1H,3H)-QUINAZOLINEDIONE, 3-AMINO-1-CYCLOPROPYL-6,7-DIFLUORO-8-METHOXY- synthesis

5synthesis methods

Product Name:2,4(1H,3H)-QUINAZOLINEDIONE, 3-AMINO-1-CYCLOPROPYL-6,7-DIFLUORO-8-METHOXY-
CAS Number:351368-41-7
Molecular formula:C12H11F2N3O3
Molecular Weight:283.23

112811-64-0
8 suppliers
inquiry

2,4(1H,3H)-QUINAZOLINEDIONE, 3-AMINO-1-CYCLOPROPYL-6,7-DIFLUORO-8-METHOXY-

351368-41-7
5 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: 1,2-dichloro-ethane / 4 h / Heating
1.2: 90 percent / dioxane / 4 h / 0 - 20 °C
2.1: 84 percent / potassium bis(trimethylsilyl)amide; 18-crown-6 / tetrahydrofuran; toluene / 1.5 h / Heating
3.1: 89 percent / sodium hydride; (2,4-dinitro-phenyl)-hydroxylamine / tetrahydrofuran / 1.5 h / Heating

References:

Tran, Tuan P.;Ellsworth, Edmund L.;Watson, Brian M.;Sanchez, Joseph P.;Showalter, H. D. Hollis;Rubin, John R.;Stier, Michael A.;Yip, Judy;Nguyen, Dai Q.;Bird, Paul;Singh, Rajeshwar [Journal of Heterocyclic Chemistry,2005,vol. 42,# 4,p. 669 - 674]

2,4(1H,3H)-Quinazolinedione, 1-cyclopropyl-6,7-difluoro-8-methoxy-

351367-87-8
1 suppliers
inquiry

33543-55-4
62 suppliers
inquiry

351368-41-7
5 suppliers
inquiry

References

351367-87-8
1 suppliers
inquiry

351368-41-7
5 suppliers
inquiry

References

112811-65-1
229 suppliers
$6.00/5g

351368-41-7
5 suppliers
inquiry

References

2,4,5-Trifluoro-3-methoxybenzoyl chloride

112811-66-2
173 suppliers
$9.00/5g

351368-41-7
5 suppliers
inquiry

References