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ChemicalBook CAS DataBase List 2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE
35711-47-8

2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: toluene-4-sulfonic acid; silica gel / neat (no solvent) / 180 °C / Microwave irradiation
2.1: trichlorophosphate / 0.25 h / 20 °C / Inert atmosphere
2.2: 3 h / 100 °C / Inert atmosphere

References:

Murugesan, Dinakaran;Mital, Alka;Kaiser, Marcel;Shackleford, David M.;Morizzi, Julia;Katneni, Kasiram;Campbell, Michael;Hudson, Alan;Charman, Susan A.;Yeates, Clive;Gilbert, Ian H. [Journal of Medicinal Chemistry,2013,vol. 56,# 7,p. 2975 - 2990]

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