3,4,5-trimethoxy-alpha-(1-methylethyl)phenylacetonitrile synthesis

1synthesis methods

Yield:-

Reaction Conditions:

with sodium amide1.) THF, 0.5 h, room temp. 2.) THF, 4 h, room temp.;Yield given. Multistep reaction;

References:

Mitani;Yoshida;Sakurai;Morikawa;Iwanaga;Koshinaka;Kato;Ito [Chemical and Pharmaceutical Bulletin,1988,vol. 36,# 1,p. 373 - 385]

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