2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid synthesis
- Product Name:2-(7-Fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
- CAS Number:393509-22-3
- Molecular formula:C13H12FNO2
- Molecular Weight:233.24
20826-94-2
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Yield:-
Steps:
11.1 (+/-) 2-(7-fluoro-1,2,3-trihydrocyclopenta[2,3-b]indol-3-yl)acetic acid
Step 1 (+/-) 2-(7-fluoro-1,2,3-trihydrocyclopenta[2,3-b]indol-3-yl)acetic acid The ethyl ester of the title compound was prepared from 10.00 g of 4-fluoro-2-iodophenylamine and 6.57 g of ethyl 2-(2-oxocyclopentyl)acetate according to example 1, step 2, to yield 5.36 g of a yellow solid. 1H NMR (acetone-d6) δ9.76 (1H, br s), 7.34 (1H, dd), 7.03 (1H, d), 6.78 (1H, td), 4.14 (2H, q), 3.57 (1H, m), 2.85-2.55 (5H, m), 2.15 (1H, m), 1.22 (3H, t).
References:
Merck Frosst Canada & Co. US6410583, 2002, B1
![Ethyl 2-(7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetate](/CAS/20150408/GIF/393509-21-2.gif)
393509-21-2
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393509-22-3
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![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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393509-22-3
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20826-94-2
173 suppliers
$26.00/1g
393509-22-3
6 suppliers
inquiry
61272-76-2
197 suppliers
$9.00/5g
393509-22-3
6 suppliers
inquiry