(3R)-2,2,2-TRIFLUORO-N-PYRROLIDIN-3-YL-ACETAMIDE synthesis

Yield:499774-45-7 100%

Reaction Conditions:

with ammonium formate;palladium on activated charcoal in ethanol; for 2 h;Heating;

References:

Hudson, Sarah;Kiankarimi, Mehrak;Rowbottom, Martin W.;Vickers, Troy D.;Wu, Dongpei;Pontillo, Joseph;Ching, Brett;Dwight, Wesley;Goodfellow, Val S.;Schwarz, David;Heise, Christopher E.;Madan, Ajay;Wen, Jenny;Ban, William;Wang, Hua;Wade, Warren S. [Bioorganic and Medicinal Chemistry Letters,2006,vol. 16,# 18,p. 4922 - 4930]