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4-(2-chloropyridin-3-yl)morpholine synthesis

6synthesis methods
110-91-8 Synthesis
Morpholine

110-91-8
672 suppliers
$9.00/1g

78607-36-0 Synthesis
2-Chloro-3-iodopyridine

78607-36-0
350 suppliers
$14.00/1g

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Yield:54231-44-6 84%

Reaction Conditions:

with palladium diacetate;caesium carbonate;2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl in toluene; for 17 h;Heating;

References:

Meyers, Caroline;Maes, Bert U. W.;Loones, Kristof T. J.;Bal, Gunther;Lemiere, Guy L. F.;Dommisse, Roger A. [Journal of Organic Chemistry,2004,vol. 69,# 18,p. 6010 - 6017]