4-(3-METHOXY-BENZYL)-PIPERIDINE synthesis
- Product Name:4-(3-METHOXY-BENZYL)-PIPERIDINE
- CAS Number:150019-61-7
- Molecular formula:C13H19NO
- Molecular Weight:205.3
![4-[(3-Methoxyphenyl)methyl]pyridine](/CAS/GIF/35854-37-6.gif)
35854-37-6
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150019-61-7
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Yield:150019-61-7 88%
Reaction Conditions:
in water;acetic acid;
Steps:
1.3 Step 3
Step 3 A mixture of 4-(3-methoxybenzyl)pyridine (25 g, 126 mmol) and platinum oxide (2.4 g) in acetic acid (250 ml) was hydrogenated for 2 hr. The catalyst was removed and the solution concentrated in vacuo. The residue was dissolved in water and the solution basified with sodium hydroxide. The basic mixture was extracted with ether. The extracts were dried and concentrated in vacuo. The residue was vacuum distilled to give 4-(3-methoxy-benzyl)piperidine as an oil (22.6 g, 88%). A sample of the hydrochloride was prepared in ether (mp: 146°-147° C.).
References:
US5530012,1996,A
874-98-6
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150019-61-7
44 suppliers
$165.00/500mg
72311-12-7
2 suppliers
inquiry
150019-61-7
44 suppliers
$165.00/500mg