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149680-95-5

4,4,4-trifluoro-3-phenylbutanoic acid synthesis

5synthesis methods
2-Butenoic acid, 4,4,4-trifluoro-3-phenyl-, (2E)-

149819-78-3
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4,4,4-trifluoro-3-phenylbutanoic acid

149680-95-5
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Yield:149680-95-5 92%

Reaction Conditions:

with hydrogen;palladium on activated charcoal in methanol; under 760 Torr; for 18 h;

References:

Carceller, Elena;Merlos, Manuel;Giral, Marta;Almansa, Carmen;Bartroli, Javier;et al. [Journal of Medicinal Chemistry,1993,vol. 36,# 20,p. 2984 - 2997]