4-(4-Ethylpiperazin-1-ly)aniline synthesis
- Product Name:4-(4-Ethylpiperazin-1-ly)aniline
- CAS Number:115619-01-7
- Molecular formula:C12H19N3
- Molecular Weight:205.3
115619-00-6
115619-01-7
General procedure: 1-ethyl-4-(4-nitrophenyl)piperazine (7.5 mmol) was dissolved in ethanol (50 mL) and 10% Pd/C catalyst (0.2 g) was added. The reaction mixture was stirred at room temperature and under hydrogen atmosphere for 9 hours. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration. The filtrate was concentrated under high vacuum to give the target product 4-(4-ethyl-1-piperazinyl)aniline.
5308-25-8
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$15.00/5 g
115619-01-7
147 suppliers
$7.00/250mg
Yield:-
Steps:
Multi-step reaction with 2 steps
1: palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 90 °C / Inert atmosphere
2: palladium 10% on activated carbon; hydrogen / 2585.81 Torr
References:
Nguyen, Thuy;Sakasegawa, Yuji;Doh-Ura, Katsumi;Go, Mei-Lin [European Journal of Medicinal Chemistry,2011,vol. 46,# 7,p. 2917 - 2929]
115619-00-6
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$14.00/250mg
115619-01-7
147 suppliers
$7.00/250mg
586-78-7
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$14.00/5g
115619-01-7
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$7.00/250mg
350-46-9
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$10.60/1gm:
115619-01-7
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$7.00/250mg
636-98-6
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115619-01-7
147 suppliers
$7.00/250mg