
4,5-Dimethyl-1,2-oxazol-3-amine hydrochloride synthesis
- Product Name:4,5-Dimethyl-1,2-oxazol-3-amine hydrochloride
- CAS Number:195447-71-3
- Molecular formula:C5H9ClN2O
- Molecular Weight:148.59

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195447-71-3
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Yield:-
Reaction Conditions:
with hydrogenchloride in 1,4-dioxane at 20; for 5 h;
Steps:
1.A
A. 4,5-Dimethyl-3-isoxazolamie hydrochloride To (4,5-dimethyl-3-isoxazolyl)carbamic acid 1,1-dimethylethyl ester (25.0 g, 117.79 mmol, prepared as described in Konoike, T. et al.,Tet. Lett., 37, 3339-3342 (1996)) in a flask, 100 ml 4N HCl in dioxane was added. The mixture was stirred at room temperature for 5 hrs and concentrated to give the title product of this step as a solid which was used in the next step without further purification.
References:
EP996618,2003,B1 Location in patent:Page/Page column 5