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ChemicalBook CAS DataBase List 4-(5-METHYL-1,3,4-OXADIAZOL-2-YL)BENZOIC ACID
892502-28-2

4-(5-METHYL-1,3,4-OXADIAZOL-2-YL)BENZOIC ACID synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: triethylamine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / N,N-dimethyl-formamide / 20 °C
2: p-toluenesulfonyl chloride; triethylamine / dichloromethane / 0 - 20 °C
3: sodium hydroxide; water / methanol / 20 °C

References:

WO2016/178092,2016,A2